Shinji Kawabata Selected Research

Glioma (Gliomas)

5/2022	Boron neutron capture therapy and add-on bevacizumab in patients with recurrent malignant glioma.
1/2022	Boron neutron capture therapy using dodecaborated albumin conjugates with maleimide is effective in a rat glioma model.
11/2021	Chronic pathophysiological changes in the normal brain parenchyma caused by radiotherapy accelerate glioma progression.
1/2021	Accelerator-based BNCT for patients with recurrent glioblastoma: a multicenter phase II study.
12/2020	The Therapeutic Effects of Dodecaborate Containing Boronophenylalanine for Boron Neutron Capture Therapy in a Rat Brain Tumor Model.
1/2019	Folate receptor-targeted novel boron compound for boron neutron capture therapy on F98 glioma-bearing rats.
12/2018	Boron Neutron Capture Therapy Combined with Early Successive Bevacizumab Treatments for Recurrent Malignant Gliomas - A Pilot Study.
12/2018	5-Aminolevulinic acid-mediated photodynamic therapy can target human glioma stem-like cells refractory to antineoplastic agents.
3/2018	Assessment of safety of 5-aminolevulinic acid-mediated photodynamic therapy in rat brain.
1/2018	Boron Neutron Capture Therapy of Malignant Gliomas.

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Shinji Kawabata Research Topics

Disease

39	Neoplasms (Cancer) 01/2022 - 11/2003
38	Glioma (Gliomas) 05/2022 - 09/2005
19	Brain Neoplasms (Brain Tumor) 01/2022 - 01/2006
14	Necrosis 05/2022 - 09/2008
14	Glioblastoma (Glioblastoma Multiforme) 05/2022 - 11/2003
8	Meningioma (Meningiomas) 01/2022 - 07/2007
4	Edema (Dropsy) 07/2015 - 11/2011
3	Pain (Aches) 04/2022 - 04/2015
2	Cysts 01/2022 - 01/2021
2	Hydrocephalus (Hydrocephaly) 01/2022 - 08/2019
2	Aneurysm (Aneurysms) 01/2020 - 03/2006
2	Neoplasm Metastasis (Metastasis) 01/2020 - 10/2007
2	Compression Fractures (Compression Fracture) 01/2016 - 04/2015
2	Inflammation (Inflammations) 12/2015 - 07/2014
2	Head and Neck Neoplasms (Head and Neck Cancer) 01/2015 - 08/2012
1	Radiation Injuries (Radiation Sickness) 05/2022
1	Disease Progression 05/2022
1	Lung Neoplasms (Lung Cancer) 04/2022
1	Urination Disorders 04/2022
1	Breast Neoplasms (Breast Cancer) 01/2022
1	Ulcerative Colitis 01/2022
1	Pulmonary Tuberculosis 01/2022
1	Lymphoma (Lymphomas) 12/2021
1	Brain Edema (Cerebral Edema) 01/2021
1	Central Nervous System Cysts (Suprasellar Cyst) 01/2021
1	Adenocarcinoma of Lung 01/2020
1	Headache (Headaches) 01/2019
1	Normal Pressure Hydrocephalus 01/2019
1	Infections 01/2019
1	Obesity 01/2019
1	Rupture 01/2019
1	Congenital Abnormalities (Deformity) 01/2019
1	Ischemic Stroke 02/2018
1	Critical Illness (Critically Ill) 06/2017
1	Stroke (Strokes) 06/2017
1	Brain Diseases (Brain Disorder) 12/2015

Drug/Important Bio-Agent (IBA)

18	BoronIBA 01/2022 - 12/2005
12	Bevacizumab (Avastin)FDA Link 05/2022 - 05/2011
6	Boron-10IBA 01/2020 - 05/2008
6	SodiumIBA 01/2017 - 12/2005
6	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 12/2015 - 11/2011
5	1-phenyl-3,3-dimethyltriazene (PDT)IBA 12/2018 - 01/2011
5	AcidsIBA 12/2018 - 09/2013
5	protoporphyrin IXIBA 12/2018 - 09/2013
3	Therapeutic UsesIBA 12/2020 - 11/2014
3	Amino Acids FDA Link 01/2017 - 03/2013
3	Monoclonal AntibodiesIBA 05/2008 - 06/2006
2	Proteins (Proteins, Gene)FDA Link 01/2022 - 11/2021
2	dodecaborateIBA 01/2022 - 12/2020
2	Methotrexate (Mexate)FDA LinkGeneric 12/2021 - 01/2006
2	Phenylalanine (L-Phenylalanine)FDA Link 12/2021 - 07/2009
2	GadoliniumIBA 01/2021 - 08/2013
2	SolutionsIBA 12/2017 - 03/2006
2	ChemokinesIBA 12/2015 - 07/2014
2	CytokinesIBA 12/2015 - 07/2014
2	Temozolomide (Temodar)FDA LinkGeneric 12/2011 - 08/2009
2	PorphyrinsIBA 06/2011 - 01/2011
2	Liposomes (Liposome)IBA 05/2011 - 05/2008
2	Transferrin (beta 2 Transferrin)IBA 05/2011 - 05/2008
2	FluoridesIBA 08/2009 - 09/2008
2	ErbB Receptors (EGF Receptor)IBA 02/2007 - 01/2006
2	Cetuximab (Erbitux)FDA Link 02/2007 - 01/2006
2	Boron CompoundsIBA 07/2006 - 12/2005
1	Biological ProductsIBA 01/2022
1	maleimideIBA 01/2022
1	Immunosuppressive Agents (Immunosuppressants)IBA 01/2022
1	AlbuminsIBA 01/2022
1	SteroidsIBA 01/2022
1	salicylhydroxamic acid (SHAM)IBA 11/2021
1	AmidesIBA 12/2020
1	Folic Acid (Vitamin M)FDA LinkGeneric 01/2019
1	Messenger RNA (mRNA)IBA 12/2018
1	EnzymesIBA 12/2018
1	Antineoplastic Agents (Antineoplastics)IBA 12/2018
1	Prealbumin (Transthyretin)IBA 06/2017
1	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 12/2015
1	InterleukinsIBA 12/2015

Therapy/Procedure

50	Boron Neutron Capture Therapy 05/2022 - 11/2003
17	Radiotherapy 01/2022 - 11/2003
10	Therapeutics 05/2022 - 01/2006
4	Photochemotherapy (Photodynamic Therapy) 12/2018 - 01/2011
4	Drug Therapy (Chemotherapy) 07/2009 - 10/2007
3	Neutron Capture Therapy 10/2018 - 06/2011
2	Re-Irradiation 05/2022 - 01/2021
2	Chemoradiotherapy 06/2013 - 08/2009
2	Craniotomy 09/2005 - 11/2003
1	Aftercare (After-Treatment) 04/2022
1	Endoscopes 01/2022
1	Cerebrospinal Fluid Shunts 01/2022
1	Cyclotrons 01/2021
1	Cerebral Revascularization 01/2020
1	Ventriculostomy 08/2019
1	Cranial Irradiation 02/2019
1	Punctures 01/2019
1	Catheters 01/2019
1	Thrombectomy 02/2018
1	Computer-Assisted Surgery (Image Guided Surgery) 12/2017
1	Lasers (Laser) 12/2017
1	Nuclear Reactors 07/2016
1	Vertebroplasty 01/2016